Quins fans ought to start getting used to the phrase 'big game'. It is a hazard of being a top of the league team.
But while Quins fans might still be coming to terms with increasing TV coverage, packed-out crowds and England call-ups, the players under the direction of Conor O'Shea seem remarkably composed.
Just as well, as this Saturday is another one of those big games.
In yet another number one plays number two, Leicester visit the Stoop this weekend with both teams fighting to secure a home semi-final play-off.
With a five point lead some may believe that the pressure is off Quins. I can assure you it's not.
Despite securing a play-off place last weekend, with an impressive win over an inexperienced Wasps side, a loss of concentration can be the difference between finishing first or third this season.
Given that a difficult trip to Sale awaits Quins in round 22, their last game at Edgeley Park, Chris Robshaw's men will want to secure top spot in the Aviva Premiership with a game to spare and a chance to relax big name players ahead of the semi-finals.
This is of course easier said than done.
Leicester find themselves coming into form with a squad that looks remarkably fresh and buoyant after their win away at Northampton last week.
And you can understand why. In their last four Aviva Premiership games, Tigers have scored a total of 154 points.
But there is much more at stake this weekend than a possible five points. There are grudges to settle and points to prove.
If Danny Care can stay out of trouble off the pitch, then he should give Ben Youngs problems on it. Struggling for form, the Tigers scrum half is fighting for his place on the plane to South Africa. Getting a hand over Youngs this Saturday should be enough to get Care a seat.
In the forwards, George Robson must have felt gutted to have missed out so narrowly on being involved in England's Six Nations, only to witness Parling look like he has cemented himself in the new set up. Watch out for some massive collisions at the breakdown.
But perhaps the biggest challenge will be at 10. Having been jilted by the England team, Flood is finding form just when Tigers need it most with ball in hand and from the boot.
At the same time, Nick Evans - back from injury to face the Tigers - has struggled in recent months.
With an afternoon kick-off both sides will hope for fine weather and an opportunity to play running and expansive rugby.
With so much at stake, at club and personal level, we might just see fireworks by the end of the day.